It is an incredibly exciting process, starting with the development of a developing egg cell in the female body, with the male sperm cell. Such an exciting process has become possible in the laboratory environment outside of the human body.
We now know some of the factors that prevent a person from fertilization and fertilized eggs. If we can not obtain pregnancy by natural means, we can combine egg cells and semen in the laboratory environment and perform the stages of early division of fertilized egg (zygote) in the laboratory, if necessary, examine them for genetic injuries,
is now an ordinary occasion. However, there are still many unknowns to continue lighting studies. The studies on infertility diagnosis and treatment have been going on since primitive times. However, serious, convincing, scientific first animal experiments began in 1891. Successful ovulation induction and subsequent gonadotropin hormones were first described by Gemzell and colleagues in 1958 by obtaining cadaveric hypophysis. But it was quite difficult in this way. It was later started to be obtained from the urine of menopausal women with high gonadotropin levels. The difficulties of finding menstrual wastes, which are the natural substance of gonadotropins obtained in this way, low purity, complete failure of source control, tedious urine collection work, LH contamination in FSH preparations had a number of disadvantages, such as the risk of differences from one product to another, and low specific activity. For this reason, scientists have tried to obtain gonadotropins in different ways and have succeeded in producing gonadotropins by using recombinant DNA technology. The pure FSH preparations produced in this way were produced in 1995 and were produced in a laboratory environment under a complete quality control system to remove all potential hazards that may arise in old gonadotropin preparations. Studies have shown that this drug can be used in fewer doses to produce more eggs in a shorter time and that a larger number of pregnancies can be achieved. Several preparations have been introduced over time, such as recombinant LH, recombinant HCG, produced using recombinant DNA technology.
Infertility research In 1968, Steptoe and Edwards met in a completely different area of meeting and transferring experiences. Since then, the work has gained great momentum, and for the first time on July 25, 1978, the human egg cell, taken from mother through laparoscopy for the first time, fertilized the sperm outside and placed the womb on the InVitro Fertilization baby (IVF).
In 1983, when embryos were frozen and stored during IVF and there was no pregnancy in the month of operation, these embryos were solved in the next months and the first pregnancy was obtained by the mother’s uterus and the total pregnancy rates rapidly increased with this method.
After that, collecting steps may be difficult for all of us. Cloning (a new copy of their human cells), and even where one is not surprised the baby’s development in the future outside the womb. But today is how it comes together. Our goal is to understand this step in a dille is to tell you.